Swathi. S2,
B. Swathi1, Kasireddy Swapna2,
G. Venkateshwarlu2, B. Swathi1, Sharada.
N2,
P. Laxmi.
S2
1Department
of Pharmacy, Palamuru University, Mahabubnagar,
Telangana, India
2Venkateshwara
Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda, Telangana, India
ABSTRACT:
Now a day’s peoples are completely habituated for
cool life or without hard work so this reason causes many diseases. Recently
most of the software employees yield for spondilysis, gastritis, heart stroke, brain stroke and
paralysis etc. especially throughout world youth suffering with stress
condition and money earning pressure and restless work, mechanical life also
causes various diseases. Recently in Nalgonda one survey
held on brain stroke and kidney failure, paralysis. In that survey as a
pharmacist and other doctors are conducted for every 100 persons participated
in that 7 members are heart stroke, 5 persons are kidney failure, 3 are paralyzed
persons are there. This survey carried at Government hospital, Gollguda, Nalgonda, Telangana. why this ailments are
raising means lack of exercise, fast food eating, environmental pollution,
restless life, insomnia, companies task pressure on employ along with lot of
reasons are there.
KEY WORDS: Heart stroke, kidney failure, paralysis, disease
survey
INTRODUCTION:
Present
life style is entirely mechanical life which causes various kinds of incurable
diseases is produced in body. With this reason peoples are struggling with
health problem, environmental pollution, food habits, lack of exercise so many
reasons are there, not only these factors including genetic or hereditary
problem. At present situation peoples are completely depend on readymade life.
Stroke is some time referred to as cerebrovascular
accident or loss of brain function due to disturbances in blood supply to the
brain or lack of blood supply is called ischemia as a result hemorrhage [1-4].
Kidney failure is medical
condition in which kidney fails to adequately filter waste products from the
blood, renal failure is mainly determined by decrease in glomerular
filtration rate when it is occur kidney failure. Paralysis is loss of muscle
function for one or more muscle in these conditions in neuron nurochemical released interrupted for this reason muscle
function ceased. Some time all above diseases come with stress conditions and
psychological feeling insistent of soul and emotional conditions, restless life
developed heart stroke, paralysis, renal failure etc[5-7].
Now a days younger’s only suffering with these disorders
due to in coordination of brain. The symptoms often intensify over the
following hours and may vary depending of which area of the brain is affected.
The brain is divided into two cerebral hemispheres (halves) and each cerebral hemisphere controls
the opposite side of the body. A blood clot in the left part of the brain will
therefore give symptoms in the right arm and leg. Typical symptoms of a stroke
are: Paralysis of an arm or a leg Paralysis [8-10] of one half of the body or
face, Blindness in one half of the field of vision, Unintelligible speech or
problems understanding, Tingling or numbness in parts of the body, dizziness and possibly fainting ,Balance and coordination problem.
Mechanism
of brain stroke, kidney failure and paralysis:
A stroke occur when there is interruption of the blood supply to a
particular area of the brain, ultimately leading to cell injury and cell death.
A stroke occurs when there is interruption of the blood supply to a particular
area of the brain, ultimately leading to cell injury and cell death. Strokes
occur when there is an occlusion of blood vessel impairing the flow blood to
the brain. When large amounts of toxins are
suddenly released in the blood
circulation after a long compressed limb is
suddenly relieved from the pressure obstructing the blood flow through its
tissues, causing ischemia. The
resulting overload can lead to the clogging and the destruction of the kidneys. It is are perfusion injury that
appears after the release of the crushing pressure. The mechanism is believed
to be the release into the bloodstream of muscle breakdown products – notably myoglobin, potassium, and phosphorus – that are the products of rhabdomyolysis.
The specific action on the kidneys is not fully understood, but may be due in
part to nephrotoxic metabolites of myoglobin.
Renal failure is mainly determined by a decrease in glomerular
filtration rate, the rate at which blood is filtered in the glomeruli
of the kidney. This is detected by a decrease in or absence
of urine production or determination
of waste products (creatinine or urea)
in the blood. Depending on the cause, hematuria (blood loss in the urine) and proteinuria (protein loss in the urine) may be noted.
|
Diseased
kidney I- frontal lobe; II-
temporal lobe; III- tissue
starved oxygen or oxygen blocked area; IV -
blood clotted |
Urethra Granular surface of the kidney
High urine
protein Granular
surface Smaller size Decreased size
of function Granular
surface of the kidney |
Graphical
representation of brain stroke, kidney failure and paralysis
CONCLUSION:
From this survey we concluded that people in urban areas are suffering
from these ailments more than rural areas because people in urban areas are
subjected to various factors like food habits, environmental pollution, brain
stroke, stress conditions, loss of exercise. From the graphical representation
highest ratios are seen in brain stroke and kidney failure. Doing exercise and
taking proper diet from time to time food intake and proper sleeping keep the
good health. If all these factors are controlled then people will lead a
healthy and happy life.
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Received on 17.12.2014 Accepted
on 05.01.2015
© Asian Pharma Press All
Right Reserved
Asian J. Pharm. Res. 5(1): Jan.-Mar. 2015; Page 48-50
DOI: 10.5958/2231-5691.2015.00007.6